
Research Interests
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Production of fuels and value-added chemicals from photosynthetic microorganisms
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Fermentative metabolism
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Advanced metabolic analysis and synthetic biology
Areas of Expertise
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Metabolomics, lipidomics, and fluxomics
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Mass spectrometry-based metabolite analysis
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Isotope tracer analysis and flux modeling
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Molecular biology and biochemistry of cyanobacteria
Education
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Ph.D., Biology, Tsinghua University, 2006–2010
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M.S., Microbiology, Central China Agricultural University, 2002–2005
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B.S., Microbiology, Central China Agricultural University, 1998–2002
Professional Experience
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Director's Postdoctoral Fellow, National Renewable Energy Laboratory, Biosciences Center, 2013–present
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Research Associate, Arizona State University, School of Life Sciences, 2010–2013
Featured Publications
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"The plasticity of cyanobacterial metabolism supports direct CO2 conversion to ethylene," Nature Plants (2015)
Highlighted by Ducat, Nature Plants, 2015.
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"Phosphoketolase pathway contributes to the carbon metabolism in cyanobacteria," Nature Plants (2015)
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"CO2-fixing one-carbon metabolism in a cellulose-degrading bacterium Clostridium thermocellum," PNAS (2016)
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"Engineered xylose utilization enhances bio-products productivity in the cyanobacterium Synechocystis PCC 6803," Metabolic Engineering (2015)
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"Genome-based metabolic mapping and 13C flux analysis reveal systematic properties of an oleaginous microalga Chlorella protothecoides," Plant Physiology (2015)
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"The -aminobutyric acid shunt contributes to closing the tricarboxylic acid cycle in Synechocystis sp. PCC 6803," Molecular Microbiology (2014)
Additional Publications
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"Ethylene forming enzyme and bio-ethylene production," Biotechnology for Biofuels (2014)
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"13C-Tracer and Gas Chromatography-Mass Spectrometry Analyses Reveal Metabolic Flux Distribution in Oleaginous Microalga Chlorella protothecoides," Plant Physiology (2010)
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"Double CO2 fixation in photosynthesis–fermentation model enhances algal lipid synthesis for biodiesel production," Bioresource Technology (2010)
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"Effect of UV-C on algal evolution and difference of growth rate, pigments and photosynthesis between prokaryotic and eukaryotic algae," Photochemistry and Photobiology (2009)
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"Identification of the proteomic changes in Synechocystis sp. PCC 6803 following prolonged UV-B irradiation," Journal of Experimental Botany (2009)
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"Action Spectra of chlorophyll a biosynthesis in cyanobacteria: dark-operative protochlorophyllide oxidoreductase-deficient mutants," Zeitschrift für Naturforschung (2009)
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"Rapid quantitation of lipid in microalgae by time-domain nuclear magnetic resonance," Journal of Microbiological Methods (2008)
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"High-density fermentation of microalga Chlorella protothecoides in bioreactor for microbio-diesel production," Applied Microbiology and Biotechnology (2008)
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"Construction of the conjugal transfer system of Streptomyces cinnamonensis and effect of PCR-mediated nsdA gene disruption on its secondary metabolism," Chinese Journal of Agricultural Biotechnology (2007)
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"Application of integrative expression of orfX gene in the industrial breeding of Streptomyces avermitilis," Chinese Journal of Agricultural Biotechnology (2007)
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"Identification and biochemical properties of Dps (starvation-induced DNA binding protein) from cyanobacterium Anabaena sp. PCC 7120," IUBMB Life (2007)
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"Enhancement and selective production of oligomycin through inactivation of avermectin's starter unit in Streptomyces avermitilis," Biotechnology Letters (2006)
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"Construction of Streptomyces avermitilis bkdF- Mutant Using PCR-mediated Gene Replacement Method," Chinese Journal of Agricultural Biotechnology (2005)
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"Research on the role of Bacillus subtilis in purifying Penaeus monodon mariculture water," Journal of Central China Agricultural University (2002)
View all NREL Publications for Wei Xiong.