Researcher Spotlight: Violeta Sanchez i Nogue’s Journey to Bioprocess Development at NREL

July 15, 2025 | By Anna Nixon | Contact media relations

Share

On a Christmas morning in the early 1990s, in a small town north of Barcelona, a young Violeta Sanchez i Nogue’s interest in chemistry was born. She unwrapped a junior chemistry lab kit that would ignite a love of science and lead to a successful career as a senior researcher at NREL.

“With the kit, you could run lots of different assays inside glass tubes with different chemical compounds,” Sanchez i Nogue said. “It even had an alcohol burner! In retrospect probably not the safest game, but you can imagine lots of color changes and fume generation when reactions were taking place. I had lots of fun playing with this game with my sister, and I was just fascinated by it.”

With visions of someday working in a chemistry lab, Sanchez i Nogue took an opportunity to expand her horizons by joining an engineering boot camp during the summer before high school graduation.

“I really enjoyed it, as it gave me exposure to university-level research," she said. "We spent a couple of weeks taking environmental samples in the Pyrenees and analyzing them in a lab the university had installed at the mountain hostel. Most of the researchers were from the chemical engineering department, so I had the chance to learn about the types of research they were doing.”

Combining Scientific Passions

Needless to say, she was hooked. She decided to combine her two interests and pursue a degree in chemical engineering at the Autonomous University of Barcelona. During her undergraduate studies, she completed an internship at Lund University in Sweden, where she later returned to earn a Ph.D. in engineering. It was here that she became familiar with NREL’s leading work on lignocellulosics and bioethanol—the focus of her thesis.

Sanchez i Nogue worked for a startup company developing yeast strains and processes for second-generation ethanol and other biotech applications. In the summer of 2015, she joined NREL as a postdoctoral researcher working on a project to produce renewable carbon fibers.

“It just felt like a once-in-a-lifetime opportunity when a colleague from grad school sent me the job posting," Sanchez i Nogue said. "It was a relatively big project with universities, other national labs, and industrial partners. This first project was ambitious, and the fermentations I was running were really fast, but it was an amazing experience to be able to work with a highly multidisciplinary team. After a few months of being at NREL, I had the opportunity to join another project, which I am still part of.”

Working With Microorganisms

“While one might think the challenges an organism faces when we put them in bioreactors are really different compared to their native environment, you can actually leverage lots of natural strengths and weaknesses from learning about their origins,” Sanchez i Nogue said.

Most of her projects have parallel efforts across the laboratory in metabolic engineering, separations, catalysis, and analysis.

“Working on multidisciplinary projects with people who all have unique sets of expertise and backgrounds can be challenging at times," Sanchez i Nogue said. "But it always feels like a pivotal moment when synergies occur because people work together.”

“I love the fact that I learn something new every single day," she said. "I have what I consider one of the greatest privileges in a job: I work with dedicated, hard-working, and kind people, and this is a pleasure not everyone has.”

Seeking New Challenges

While the development of core capabilities happens on a laboratory scale, Sanchez i Nogue also works at the pilot scale in NREL’s Integrated Biorefinery Research Facility and externally with different industrial and university project partners.

Given her proclivity for collaboration, Sanchez i Nogue is not one to shy away from a new challenge. In 2023, she worked to onboard new operations in NREL’s Field Test Laboratory Building to be able to use different types of organic waste (including food waste, manure, and wastewater). Today, she is doing similar work on setting up an aerobic gas fermentation system in NREL’s new Research and Innovation Laboratory that will allow the use of hydrogen, oxygen, and flue gases.

“Deploying new capabilities in the lab is often challenging,” Sanchez i Nogue said. “Who do we bring to the table to help moving things forward? How does it fit into the current lab operations? Which changes will be needed to implement it safely? It is a lot of work behind the scenes.”

Sanchez i Nogue’s behind-the-scenes work has a history of paying off.

“Over these last years, I have been fortunate to work with people who took our challenges as theirs, and that has allowed for instrumental changes to the system,” she said. “I am happy to contribute to expanding NREL’s bioeconomy and sustainable transportation research capabilities!”

Living Beyond the Lab

Outside of work, Sanchez i Nogue enjoys cooking, baking, reading, gardening, and raising her 2-year-old daughter, which includes answering endless whys about people and nature’s curiosities.

“We recently had a nice opportunity to see a couple of robins nesting in our front yard, so we talked about how and why they were constructing the nest, laying the eggs, incubating them, feeding them, teaching them to fly, and more,” she said. “She is also fascinated by butterflies and has just started to distinguish ants from spiders.”

Her daughter’s expanding love of learning about the world around her mirrors that of her own, nurtured by the fateful junior chemistry lab kit from many Christmases ago.