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Photo of Vladimir V. Lunin

Vladimir Lunin

Researcher V-Chemistry

Vladimir.Lunin@nrel.gov | 303-384-7754

Research Interests

  • Glycoside hydrolases, lyases, transferases

  • Establishing molecular mechanisms of protein-substrate interaction for enzymes involved in polysaccharide synthesis, modification, or breakdown

  • Biomass deconstruction and recalcitrance


Areas of Expertise

  • Protein purification

  • Protein crystallization

  • X-ray diffraction data collection

  • Protein structure determination

  • Obtaining structures of protein-ligand complexes

  • Site-directed mutagenesis

  • Structure-function relationship

  • Enzymatic mechanisms


Education

  • Ph.D., Chemistry, Institute of Crystallography, Russian Academy of Sciences, 2000

  • M.S., Chemistry, Moscow State University, Russia, 1997


Professional Experience

  • National Renewable Energy Laboratory, Biosciences Center, 2008present

  • University Health Network, Toronto, Canada, 20042007

  • Biotechnology Research Institute, National Research Council, Montreal, Canada, 20012004


Featured Publications

  1. "Revealing Nature's Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA," Science (2013)

  2. "Sequence, Structure, and Evolution of Cellulases in Glycoside Hydrolase Family 48," Journal of Biological Chemistry (2012)

  3. "The unique binding mode of cellulosomal CBM4 from Clostridium thermocellum cellobiohydrolase A," Journal of Molecular Biology (2010)

  4. "Discrete and Structurally Unique Proteins (Tāpirins) Mediate Attachment of Extremely Thermophilic Caldicellulosiruptor Species to Cellulose," Journal of Biological Chemistry (2015)

  5. "Crystal Structure of the CorA Mg2+ Transporter," Nature (2006)

View all NREL Publications for Vladimir V. Lunin.