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Katherine Brown

Researcher IV-Chemistry | 303-384-7721

Research Interests

Kate Brown received her Ph.D. from the Massachusetts Institute of Technology in 2008. While at the National Renewable Energy Laboratory, her research has focused on the synthesis and characterization of semiconductor nanoparticle enzyme biohybrid complexes. She has investigated complexes of CdTe, CdSe, and CdS nanoparticles and with several redox enzymes, including [FeFe]-hydrogenase from Clostridium acetobutylicum and ferredoxin NADP+ reductase.

The characterization of these complexes has focused on the thermodynamics and orientation of complex assembly, the photocatalytic activity and turnover frequency of the enzymes, the light capture charge transfer mechanisms, and the quantum yield of the complexes.

The study of these biohybrid complexes has provided new insights into how enzymes control interfacial electron transfer, as well as novel design parameters for improving productive light-driven electron transfer from nanoparticles to surface adsorbed catalysts.

Featured Publications

  1. "Diameter dependent electron transfer kinetics in semiconductor-enzyme complexes," ACS Nano (2014)

  2. "Competition between electron transfer, trapping, and recombination in CdS nanorod-hydrogenase complexes," Physical Chemistry Chemical Physics (2015)

  3. "Electron transfer kinetics in CdS nanorod-[FeFe] hydrogenase complexes and implications for photochemical H2 generation," Journal of the American Chemical Society (2014)

  4. "Characterization of photochemical processes for H2 production by CdS nanorod-[FeFe] hydrogenase complexes," Journal of the American Chemical Society (2012)

  5. "Photobiological and Photobiomimetic Production of Solar Fuels," Carbon Neutral Fuels and Energy Carriers (2011)

  6. "Catalytic turnover of [FeFe]-hydrogenase based on single-molecule imaging," Journal of the American Chemical Society (2011)

  7. "Controlled assembly of hydrogenase-CdTe nanocrystal hybrids for solar hydrogen production," Journal of the American Chemical Society (2010)

  8. "Recombinant and in vitro expression systems for hydrogenases: new frontiers in basic and applied studies for biological and synthetic H2 production," Dalton Transactions (2010)

  9. "Nucleotide-Surface interactions in DNA modified Au-nanoparticle conjugates: Sequence effects on reactivity and hybridization," Journal of Physical Chemistry C (2008)

  10. "Magnetic field heating study of Fe-doped Au nanoparticles," Journal of Magnetism and Magnetic Materials (2007)

  11. "Changes in oligonucleotide conformation on nanoparticle surfaces by modification with mercaptohexanol," Nano Letters (2004)

View all NREL Publications for Kate Brown.