Michael Ratzloff received his B.S. in Chemistry from the Colorado School of Mines in 2008, where his senior research focused on chemical education. In 2011, he received his M.S. in Materials Science, also from the Colorado School of Mines. His Master's thesis involved developing multiple infrared (IR) spectroscopic techniques to allow the study of structure/function relationships of the active site, or H-cluster, of hydrogenase enzymes.
His current research continues his thesis work, developing more advanced IR spectroscopic techniques to allow organometallic enzymes to be studied in more detail under a variety of different conditions. These studies should provide a greater level of understanding of the catalytic mechanism used by hydrogenase enzymes to produce hydrogen.
- Mulder, DW; Ratzloff, MW; Shepard, EM; Byer, AS; Noone, SM; Peters, JW; Broderick, JB; King, PW "EPR and FTIR Analysis of the Mechanism of H2 Activation by [FeFe]-Hydrogenase HydA1 from Chlamydomonas reinhardtii." Journal of the American Chemical Society (135:18); pp. 6921-6929.
- Mulder, DW; Ratzloff, MW; Bruschi, M; Greco, C; Koonce, E; Peters, JW; King, PW "Investigations on the Role of Proton-Coupled Electron Transfer in Hydrogen Activation by [FeFe]-Hydrogenase." Journal of the American Chemical Society (136:43); pp. 15394-15402.
- Swanson, KD; Ratzloff, MW; Mulder, DW; Artz, JH; Ghose, S; Hoffman, A; White, S; Zadvornyy, OA; Broderick, JB; Bothner, B; King, PW; Peters, JW "[FeFe]-Hydrogenase Oxygen Inactivation is Initiated at the H cluster 2Fe Subcluster." Journal of the America Chemical Society (135:5); pp. 1809-1816.