Hui Wei

Hui Wei

Research Scientist

Photo of Hui Wei
(303) 384-6620
At NREL Since: 


Hui Wei joined NREL in 2008, and is a Senior Scientist I in the Biomolecular Sciences Team, the Bioscience Center.  His main research interest and current research activities at NREl are focused on (1) the genetic modification of plants by overexpressing the glycoside hydrolase and biocatalysts to increase the biomass pretreatability and digestibility, (2) the genetic engineering of yeast and bacteria for the production of advanced biofuels, and (3) the biomaterials and biomanufacturing. 






In 2003, he earned a Ph.D. in Plant and Microbial Physiology from Queen's University in Canada, where he worked on the metabolism of carbon, nitrogen and oxygen, and the ion transport in the bacteria-infected plant cells. He also earned an M.S. in Microbiology from the Central China Agricultural University and a B.S. in Genetics from Wuhan University.




In accordance with his multi-disciplinary education background, Dr. Wei's research experience also covers both plant and microbial fields. He was a Postdoctoral Researcher at Iowa State University (2003-2005), where he identified novel genes and proteins involved in plant cold acclimation using functional genomics approaches. He then moved to the National Institute of Health as a Visiting Fellow (2005-2008). His research in the Wuhan Institute of Virology, Chinese Academy of Science (1988-1998) focused on the physiology and genetics of plant-microbe interactions and the industrial-scale fermentation of beneficial microorganisms. Dr. Wei has authored 45 peer-reviewed publications and is a recipient of a number of awards, including the NICHD/NIH Fellow Award.


Selected Publications 

  1. Wei, H; Yang H; Ciesielski PN; Donohoe BS; McCann MC; Murph AS; Peer WA; Ding SY; Himmel ME; Tucker MP (2015). "Transgenic ferritin overproduction enhances thermochemical pretreatments in Arabidopsis." Biomass Bioenergy (72); pp. 55-64.
  2. Wei H; Brunecky R; Donohoe, BS; Ding SY; Ciesielski, PN; Yang S; Tucker MP; Himmel ME "Identifying the ionically bound cell wall and intracellular glycoside hydrolases in late growth stage Arabidopsis stems: implications for the genetic engineering of bionergy crops." Frontiers plant science (6); p. 315.
  3. Wei H; Wang W; Tucker MP; Himmel ME; Brunecky R (2015). "Feedstock engineering and biomass pretreatments: new views for a greener biofuels process. in Direct Microbial Conversion of Biomass to Advanced Biofuels," Mike Himmel , ed. Elsevier-Science and Technology Books.
  4. Wei H; Fu Y; Magnusson L; Baker JO; Maness PC; Xu Q; Yang S; Bowersox A; Bogorad I; Wang W; Tucker MP; Himmel ME; Ding SY (2014). "Comparison of transcriptional profiles of Clostridium thermocellum grown on cellobiose and pretreated yellow poplar using RNA-Sew." Frontiers microbiol (5); p. 142.
  5. Wei H; Wang W; Alahuhta M; Vander Wall T; Baker JO; Taylor II LE; Decker SR; Himmel ME; Zhang M (2014). "Engineering towards a complete heterologous cellulase secretome in Yarrowia lipolytica reveals its potential for consolidated bioprocessing." Biotechnol Biofuels (7); p. 148.

NREL Publications 

View NREL Publications for this staff member.