Hui Wei

Hui Wei

Research Scientist

Photo of Hui Wei
(303) 384-6620
At NREL Since: 

Hui Wei joined NREL in 2008, and is a Research Scientist in the Biomolecular Sciences Team, the Bioscience Center.  His main research interest and current research activities at NREl are focused on (1) the genetic modification of plants to increase their biomas digestibility, (2) the efficient microbial conversion of bimass to biofuels, including biodiesel and other long-chain hydrocarbons, and (3) the plant-microbe interactions.

In 2003, he earned a Ph.D. in Plant and Microbial Physiology from Queen's University in Canada. During his Ph.D. studies, he worked on the metabolism of carbon, nitrogen and oxygen, and the ion transport in the bacteria-infected plant cells. He also earned an M.S. in Microbiology from the Central China Agricultural University and a B.S. in Genetics from Wuhan Univeristy.

In accordance with his multi-disciplinary education background, Dr. Wei's research experience also covers both plant and microbial fields. He was a Postdoctoral Researcher at Iowa State Univesity (2003-2005), where he identified novel genes and proteins involved in plant cold acclimation using functional genomics approaches. He then moved to the National Institute of Health as a Visiting Fellow (2005-2008). His research in the Wuhan Institute of Virology, Chinese Academy of Science (1988-1998) focused on the physiology and genetics of plant-microbe interactions and the industrial-scale fermentation of beneficial microorganisms.

As an experienced researcher in microbial and plant sciences, Dr. Wei has authored 36 peer-reviewed publications and is a recipient of a number of awards, including the NICHD/NIH Fellow Award in 2007.

Selected Publications 

  1. Wei, H.; Kim, S.J.; Zhang, Z.; Tsai, P.C.; Choi, M.S.; Wisniewski, K.E.. Mukherjee, A.B. (2008). "ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones.." Human Mol Genet (17); pp. 469-477.
  2. Wei, H.; Fu, Y.; Arora, R. (2006). "Utilization of intron-flanking EST-specific markers in the phylogenetic analysis and parentage identification of Rhododendron species and hybrids." J Am Hort Soc (131); pp. 814-819.
  3. Wei, H.; Layzell, D.B. (2006). "Adenylate-coupled ion movement. A mechanism for the control of nodule permeability to O2 diffusion." Plant Physiol (141); pp. 280-287.
  4. Wei, H.; Dhanaraj, A.L.; Rowland, L.J.; Arora, R.; Fu, Y.; Li, S. (2006). "Identification of cold acclimation-responsive Rhododendron genes for lipid metabolism, membrane transport and lignin biosynthesis: importance of moderately abundant ESTs in genomic studies." Plant Cell Environ (29); pp. 1347-1356.
  5. Brunecky, R.; Baker, J.; Wei, H.; Taylor, L.; Himmel, M.; Decker, S. (2012). "Analysis of transgenic glycoside hydrolases expressed in plants: T. reesei CBHI and A. cellulolyticus." Methods Mol Biol (908);
  6. Wei, H; Xu, Q; Taylor II, L; Baker, JO; Tucker, M; Ding, S (2009). "Natural paradigms of plant cell wall degradation." Cur Opin Biotech (20);
  7. Chen, K; Renaut, J; Sergeant, K; Wei, H; Arora, R (2012). "Proteomic changes associated with freeze-thaw injury and post-thaw recovery inonion (Allium cepa L.) scales.." Plant Cell Environ
  8. Wei, H; Tucker, MP; Baker, J; Harris, M; Luo, Y; Liu, YS, ; Xu, Q; Himmel, M; Ding, S (2012). "Tracking dynamics of biomass composting by monitoring the changes in substrate structure, microbial community, and enzyme activity.." Biotechnol Biofuels (5:20);
  9. Wei, H; Donohoe, B; Vinzant, T; Ciesielski, P; Wang, W; Gedvilas, L; Zeng, Y; Johnson, DK; Ding, S; Himmel, M; Tucker, M (2011). "Elucidating the role of ferrous ion cocatalyst in enhancing dilute acid pretreatment of lignocellulosic biomass." Biotechnol Biofuels (4:48);
  10. Wei, H; Zhang, Z; Saha, A; Peng, S; Chandra, G; Quezado, Z; Mukherjee, AB (2011). "Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.." Human Mo/Genet (20);