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Seth Noone

Research Technician

Photo of Seth Noone
Phone: 
(303) 384-7936
At NREL Since: 
2009

Seth Noone received his M.S. in Biomedical Basic Science from the University of Colorado Denver Health Sciences Center in 2009 under the supervision of Dr. Jessica Tyler. As part of his studies, he designed and performed experiments with S. cerevisiae to investigate the structure and function of a highly conserved chaperone protein that is important for the assembly and disassembly of chromatin, the DNA-protein complex integral to regulating the cellular genomic processes. Mutations were generated to allow in vivo evaluation of protein function so that the role of the phosphorylation state and the relevance of known structural changes could be investigated.

His current research at NREL involves development of the expression and reactor-scale production of native and mutant [Fe-Fe] hydrogenases from bacterial and algal organisms. Once purified, the hydrogenases are being studied to understand basic structure/function relationships, as well as how to improve their performance as catalysts in natural and artificial applications.